In 1961 a young South African, Michael Cassidy, set out on an exploratory visit to 31 cities in Africa. The trip confirmed to Michael that his calling was to work in evangelising the cities of Africa with a particular focus on the leaders in those cities.

The first city-wide mission was held the following year in Pietermaritzburg, South Africa. The mission was extraordinarily successful with many committing themselves to following Jesus. If African Enterprise was to reach the 31 cities that Michael had visited and beyond, however, they needed to overcome geographical and cultural barriers. The need for more teams became evident. A second team was established in Uganda in 1971 under the leadership of the late Bishop Festo Kivengere. As opportunities and funds became available eight other teams were established.

Today African Enterprise is a partnership of approximately 300 staff and countless volunteers and friends representing ten national teams. These teams work in mission and evangelism, reconciliation, training and social action. There are also several support offices across the globe. The ministry of African Enterprise continues to grow and impact lives in and through Christ, bringing Jesus to more than a million people in Africa each year. God has been faithful!